Eden

Emerging Diseases in a Changing european environment

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Leishmaniasis

 
Phlebotomus. © B. Pesson

State of the art

Sandfly-borne diseases - especially leishmaniasis - have persisted within Europe despite considerable control attempts. The close association of these vectors with human habitation in the Mediterranean region ensures transmission to humans from domestic and other animal reservoirs. The reduced effectiveness of existing chemotherapies (especially in cases of co-infection with HIV), the lack of any vaccine and the likelihood of spread with increasing global and environmental changes make leishmaniasis a key disease within EDEN.

 

General objectives

The objectives of EDEN-LEI are : i) to quantifying the relative roles of specific environmental and climatic factors as determinants of the abundance of vector species and races and the prevalence of strains of Leishmania infantum in humans and domestic dogs in representative field sites ii) in order to create the first pan-European risk maps of the European distributions of the diverse range of strains of Leishmania and their main vectors.

 

Teams

Natural History Museum, United Kingdom Paul READY P.Ready@nhm.ac.uk
Ege University Medical School, Turkey Yusuf OZBEL yozbel@med.ege.edu.tr
Faculty of Veterinary Science, Hungary Robert FARKAS Farkas.Robert@aotk.szie.hu
Instituto de Salud Carlos III, Spain Antonorio TENORIO atenorio@isciii.es
Instituto Superiore di Sanità, Italy Marina GRAMICCIA gramicci@iss.it
London School of Hygien & Tropical Medicine, United Kingdom Clive DAVIES Clive.Davies@lshtm.ac.uk
Universidade Nova de Lisboa, Portugal Virgilio DO ROSARIO CMDT@ihmt.unl.pt
Université Montpellier 1, France Jean-Pierre DEDET parasito@univ-montp1.fr
University of Barcelona, Spain Montserrat GALLEGO mgallego@ub.edu
University of Crete, Greece Yannis TSELENTIS tselendi@med.uoc.gr

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